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Loki (OmiCLIP)

Visual–omics foundation model aligning H&E histology with spatial transcriptomics for tissue alignment, cell-type decomposition and expression prediction.

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CategorySpatial omics
GitHubGuangyuWangLab2021/Loki
First public2025-04-16 (source)
Paperhttps://doi.org/10.1038/s41592-025-02707-1 · Nature Methods (2025)
LicenseBSD-3-Clause (non-commercial, academic use)
PricingOpen source (non-commercial)
Tags#foundation-model#histology#multimodal
Last checked2026-10-16

Specs

Platforms supportedH&E + spatial transcriptomics
Resolution—
TasksHistology–ST alignment, decomposition, expression prediction
GitHub stars151
Interface—

Specs come from each project's README, paper or official page · Loki (OmiCLIP) README · Loki (OmiCLIP) paper. “—” means we couldn't verify it.

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