← Spatial omics

DIRAC

DIRAC is a spatial omics tool whose code is published by boxiangliulab on GitHub, first public in 2026, described in Nature Methods (2026). Graph neural network that integrates spatial multi-omic data into a domain-invariant embedding and automates cell-type annotation by transferring labels across studies.

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CategorySpatial omics
Developer (GitHub)boxiangliulab
TaskVertical and horizontal integration; automated cell-type annotation via label transfer; spatial domain identification
InterfacePython package (PyTorch, Scanpy); pip install sodirac
Websitedirac-tutorial.readthedocs.io/en/latest
GitHubboxiangliulab/DIRAC
Released2026-11-05 (source)
Paperhttps://doi.org/10.1038/s41592-026-03282-9 · Nature Methods (2026)
Code licenseAGPL-3.0
License notedual licence: AGPL-3.0 for non-commercial/academic use; commercial licence available from the authors
What this allowsNon-commercial
Non-commercial use such as academic research is OK; commercial use needs a separate license from the owner. What do these mean?
License sourcegithub.com/boxiangliulab/DIRAC/blob/main/LICENSE · checked 2026-11-08
PricingOpen source (non-commercial)
Tags#spatial-multiomics#integration#graph-neural-network#cell-type-annotation
Last checked · links verified

Can I use DIRAC commercially?

No. The recorded terms do not allow commercial use without a separate license from the owner.

What the license types mean · not legal advice.

Specs

Platforms supportedSequencing-based and imaging-based spatial multi-omics, including Stereo-CITE-seq
Resolution—
TasksVertical and horizontal integration; automated cell-type annotation via label transfer; spatial domain identification
GitHub stars5
InterfacePython package (PyTorch, Scanpy); pip install sodirac

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