← Protein structure & design

RFantibody

Structure-based de novo antibody and nanobody design with fine-tuned RFdiffusion, ProteinMPNN and RF2.

Visit website ↗

CategoryProtein structure & design
GitHubRosettaCommons/RFantibody
First public2024-03-18 (source)
Paperhttps://doi.org/10.1101/2024.03.14.585103
LicenseMIT
PricingOpen source
Tags#antibody#design#diffusion
Last checked2026-10-16

Specs

TaskDe novo antibody / nanobody design
ModalitiesVHH, scFv
MSA required—
Open weightsYes
GPU need—
GitHub stars542
InterfaceDocker

Specs come from each project's README, paper or official page · RFantibody README · RFantibody paper. “—” means we couldn't verify it.

Compare with…

Pick 1–3 other Protein structure & design tools to compare side by side with RFantibody.

Select 1–3 tools

Related

Structure prediction of proteins, nucleic acids, ligands and their complexes; free web server and code, weights on request for non-commercial use.

Protein structure & designFree (research)#structure#complexes

200M+ predicted protein structures from DeepMind and EMBL-EBI.

Protein structure & designOpen source#database#structure

RFdiffusion

Diffusion model for de novo protein backbone design and binder design.

Protein structure & designOpen source#design#diffusion