BindCraft
One-shot de novo binder design pipeline with AF2 hallucination.
| Category | Protein structure & design |
|---|---|
| GitHub | martinpacesa/BindCraft |
| First public | 2024-09-29 (source) |
| Paper | https://www.nature.com/articles/s41586-025-09429-6 |
| License | MIT |
| Pricing | Open source |
| Tags | #binder#design |
| Last checked | 2026-10-16 |
Compare with… BindCraft vs RFdiffusion
Specs
| Task | Binder design |
|---|---|
| Modalities | Protein binders |
| MSA required | — |
| Open weights | Uses AlphaFold2 weights |
| GPU need | Large GPU memory needed |
| GitHub stars | 1,249 |
| Interface | Colab |
Specs come from each project's README, paper or official page · BindCraft README · BindCraft paper. “—” means we couldn't verify it.
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