← Microbiome & metagenomics

MetaPhlAn 4

Marker-gene-based taxonomic profiling of metagenomes, including uncharacterized species.

Visit website ↗

CategoryMicrobiome & metagenomics
GitHubbiobakery/MetaPhlAn
First public2023-02-23 (source)
Paperhttps://doi.org/10.1038/s41587-023-01688-w
LicenseMIT
PricingOpen source
Tags#metagenomics#profiling#taxonomy
Last checked2026-10-16

Specs

InputMetagenomic shotgun reads
TaskSpecies-level taxonomic profiling (bacteria, archaea, eukaryotes, viruses)
Reference databaseMarker genes from 1.01M reference genomes + MAGs (26,970 SGBs)
GitHub stars427
InterfacePackage, Docker

Specs come from each project's README, paper or official page · MetaPhlAn 4 README · MetaPhlAn 4 paper. “—” means we couldn't verify it.

Compare with…

Pick 1–3 other Microbiome & metagenomics tools to compare side by side with MetaPhlAn 4.

Select 1–3 tools

Related

HUMAnN 3

Functional profiling of metagenomes and metatranscriptomes (gene families and pathways).

Microbiome & metagenomicsOpen source#metagenomics#functional

Kraken 2

Fast k-mer based taxonomic classification of metagenomic reads.

Microbiome & metagenomicsOpen source#metagenomics#classification

GTDB-Tk

Assigns GTDB taxonomy to bacterial and archaeal genomes and MAGs.

Microbiome & metagenomicsOpen source#taxonomy#mags