MetaPhlAn 4 vs Kraken 2
MetaPhlAn 4: Marker-gene-based taxonomic profiling of metagenomes, including uncharacterized species. Kraken 2: Fast k-mer based taxonomic classification of metagenomic reads.
Facts below come from each project's own website, repository and paper. We don't publish benchmark claims here; see the papers for evaluations. Shared tags: metagenomics.
| Field | MetaPhlAn 4 | Kraken 2 |
|---|---|---|
| Input | Metagenomic shotgun reads | Metagenomic sequence reads |
| Task | Species-level taxonomic profiling (bacteria, archaea, eukaryotes, viruses) | k-mer taxonomic classification (+ translated search) |
| Reference database | Marker genes from 1.01M reference genomes + MAGs (26,970 SGBs) | — |
| License | MIT | MIT |
| Pricing | Open source | Open source |
| Released | 2023-02-23 | 2018-06-26 |
| Paper | Link | Link |
| GitHub | GitHub | GitHub |
| GitHub stars | 427 | 943 |
| Interface | Package, Docker | — |
License and commercial use
| Field | MetaPhlAn 4 | Kraken 2 |
|---|---|---|
| Code license | MIT | MIT |
| Weights license | — | — |
| Commercial use | Permissive (commercial OK) | Permissive (commercial OK) |
| Answer | Yes. The recorded license is permissive, so closed-source commercial use is allowed if you keep the notices. Details | Yes. The recorded license is permissive, so closed-source commercial use is allowed if you keep the notices. Details |
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