← Microbiome & metagenomics

sylph

Ultrafast species-level metagenome profiler using abundance-corrected k-mer sketching (ANI-based containment).

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CategoryMicrobiome & metagenomics
GitHubbluenote-1577/sylph
First public2023-11-20 (source)
Paperhttps://doi.org/10.1038/s41587-024-02412-y · Nature Biotechnology (2025)
LicenseMIT
PricingOpen source
Tags#profiling#k-mer#taxonomy
Last checked2026-10-16

Specs

InputMetagenomic short or long reads
TaskSpecies-level profiling + containment ANI
Reference database—
GitHub stars329
Interface—

Specs come from each project's README, paper or official page · sylph README · sylph paper. “—” means we couldn't verify it.

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