← Genomics & DNA models

tangermeme

Toolkit for using trained genomic deep learning models: batched predictions, DeepLIFT/SHAP attributions, variant effects, ablations, seqlet calling, motif annotation and DNA design.

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CategoryGenomics & DNA models
GitHubjmschrei/tangermeme
First public2024-02-04 (source)
Paperhttps://doi.org/10.1038/s41592-026-03254-z · Nature Methods (2026)
Code licenseMIT
What this allowsPermissive (commercial OK)
Use, modify and ship it inside closed-source commercial products; keep the license text and copyright notices. What do these mean?
License sourcejmschrei/tangermeme · repository
PricingOpen source
Tags#interpretability#regulatory#variant-effect#pytorch
Last checked · links verified

Can I use tangermeme commercially?

Yes. The recorded license is permissive, so closed-source commercial use is allowed if you keep the notices.

What the license types mean · not legal advice.

Specs

Input length / contextAny input length (memory-bound); any output type, from scalars to profiles
Resolution—
Species—
TasksPost-training analysis of sequence-to-function models (attribution, variant effects, seqlets/motifs, design)
GitHub stars324
InterfacePackage (pip install tangermeme)

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