RFdiffusion3
All-atom diffusion model from the Baker lab for designing protein binders to DNA, proteins and small molecules, plus enzymes; ~10x faster than RFdiffusion2.
| Category | Protein structure & design |
|---|---|
| GitHub | RosettaCommons/foundry |
| First public | 2025-12-03 (source) |
| License | BSD-3-Clause |
| Pricing | Open source |
| Tags | #protein-design#diffusion#all-atom |
| Last checked | 2026-10-16 |
Specs
| Task | All-atom protein design |
|---|---|
| Modalities | — |
| MSA required | — |
| Open weights | Yes (foundry install base-models) |
| GPU need | — |
| GitHub stars | — |
| Interface | Package (foundry) |
Specs come from each project's README, paper or official page · RFdiffusion3 README · RFdiffusion3 site · RFdiffusion3 README. “—” means we couldn't verify it.
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