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GEARS

Graph-based prediction of transcriptional outcomes of genetic perturbations.

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CategorySingle-cell & foundation models
GitHubsnap-stanford/GEARS
First public2023-08-17 (source)
Paperhttps://www.nature.com/articles/s41587-023-01905-6
LicenseMIT
PricingOpen source
Tags#perturbation#gnn
Last checked2026-10-16

Specs

Pretraining corpus—
ArchitectureDeep learning + gene–gene knowledge graph
TasksPerturbation (single and multi-gene)
Species—
GitHub stars418
InterfacePackage, Colab

Specs come from each project's README, paper or official page · GEARS README · GEARS paper. “—” means we couldn't verify it.

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