← Protein structure & design

ESM-2 / ESMFold

Protein language models and single-sequence structure prediction (Meta repo archived; models still widely used via Hugging Face).

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CategoryProtein structure & design
GitHubfacebookresearch/esm
First public2022-07-21 (source)
Paperhttps://www.science.org/doi/10.1126/science.ade2574
LicenseMIT
PricingOpen source
Tags#plm#structure
Last checked2026-10-16

Specs

TaskProtein language model, structure prediction
ModalitiesProtein (single chain)
MSA requiredNo (single sequence)
Open weightsYes
GPU need—
GitHub stars4,170
InterfacePackage, Colab

Specs come from each project's README, paper or official page · ESM-2 / ESMFold README · ESM-2 / ESMFold paper. “—” means we couldn't verify it.

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