DISCO
Diffusion model that co-designs protein sequence and structure conditioned on ligands, DNA or RNA.
| Category | Protein structure & design |
|---|---|
| GitHub | DISCO-design/DISCO |
| First public | 2026-04-07 (source) |
| License | Apache-2.0 |
| Pricing | Open source |
| Tags | #diffusion-models#enzyme-design#protein-design |
| Last checked | 2026-10-16 |
Specs
| Task | Sequence-structure co-design, binder design |
|---|---|
| Modalities | Protein with ligand/DNA/RNA |
| MSA required | No |
| Open weights | — |
| GPU need | GPU required |
| GitHub stars | 221 |
| Interface | — |
Specs come from each project's README, paper or official page · DISCO README. “—” means we couldn't verify it.
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