Chai-1
Multimodal foundation model for molecular structure prediction.
| Category | Protein structure & design |
|---|---|
| GitHub | chaidiscovery/chai-lab |
| First public | 2024-09-09 (source) |
| Paper | https://www.biorxiv.org/content/10.1101/2024.10.10.615955 |
| License | Apache-2.0 |
| Pricing | Open source |
| Tags | #structure#complexes |
| Last checked | 2026-10-16 |
Compare with… Chai-1 vs Boltz
Specs
| Task | Structure prediction |
|---|---|
| Modalities | Protein, nucleotides, ligands (SMILES), modified residues, complex |
| MSA required | Optional (single-sequence mode supported) |
| Open weights | Yes (non-commercial); free web interface incl. commercial |
| GPU need | Required: CUDA + bfloat16; A100/H100/L40S recommended |
| GitHub stars | 2,003 |
| Interface | Package, Docker, Web |
Specs come from each project's README, paper or official page · Chai-1 README · Chai-1 paper. “—” means we couldn't verify it.
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