Boltz
Open biomolecular interaction models (Boltz-1, Boltz-2) for complex structure and binding-affinity prediction.
| Category | Protein structure & design |
|---|---|
| GitHub | jwohlwend/boltz |
| First public | 2024-11-17 (source) |
| Paper | https://www.biorxiv.org/content/10.1101/2024.11.19.624167 |
| License | MIT |
| Pricing | Open source |
| Tags | #structure#affinity |
| Last checked | 2026-10-16 |
Compare with… Boltz vs AlphaFold Server (AlphaFold 3) · Boltz vs Chai-1
Specs
| Task | Structure + binding-affinity prediction |
|---|---|
| Modalities | Biomolecular complexes |
| MSA required | Optional (MSA server flag) |
| Open weights | Yes (MIT) |
| GPU need | Recommended; CPU supported but much slower |
| GitHub stars | 4,255 |
| Interface | Package |
Specs come from each project's README, paper or official page · Boltz README · Boltz paper. “—” means we couldn't verify it.
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