Casanovo vs InstaNovo
Casanovo: Transformer for de novo peptide sequencing directly from MS/MS spectra. InstaNovo: Transformer and diffusion models for de novo peptide sequencing from tandem mass spectra.
Facts below come from each project's own website, repository and paper. We don't publish benchmark claims here; see the papers for evaluations. Shared tags: de-novo, mass-spec.
| Field | Casanovo | InstaNovo |
|---|---|---|
| Acquisition (DDA / DIA) | — | — |
| Task | De novo peptide sequencing | De novo peptide sequencing (transformer + diffusion) |
| Input | MS/MS spectra | MS/MS spectra |
| License | Apache-2.0 | Apache-2.0 (code; model checkpoints CC BY-NC-SA 4.0, non-commercial weights) |
| Pricing | Open source | Open source (non-commercial) |
| Released | 2022-08-23 | 2023-09-01 |
| Paper | Link | Link |
| GitHub | GitHub | GitHub |
| GitHub stars | 204 | 135 |
| Interface | — | Colab |
License and commercial use
| Field | Casanovo | InstaNovo |
|---|---|---|
| Code license | Apache-2.0 | Apache-2.0 |
| Weights license | — | model checkpoints CC BY-NC-SA 4.0, non-commercial weights |
| Commercial use | Permissive (commercial OK) | Mixed (code vs weights differ) |
| Answer | Yes. The recorded license is permissive, so closed-source commercial use is allowed if you keep the notices. Details | Partly. The code and the weights (or hosted service) are under different terms; the restrictive part does not allow commercial use. Details |
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