ThermoMPNN
Graph neural network built on ProteinMPNN that predicts stability changes (ddG) for protein point mutations.
| Category | Protein structure & design |
|---|---|
| GitHub | Kuhlman-Lab/ThermoMPNN |
| First public | 2023-07-19 (source) |
| Paper | https://doi.org/10.1073/pnas.2314853121 · Proceedings of the National Academy of Sciences (2024) |
| License | MIT |
| Pricing | Open source |
| Tags | #protein |
| Last checked | 2026-10-16 |
Specs
| Task | Stability (ddG) prediction |
|---|---|
| Modalities | Protein structure |
| MSA required | No |
| Open weights | Yes |
| GPU need | CPU or GPU |
| GitHub stars | 276 |
| Interface | — |
Specs come from each project's README, paper or official page · ThermoMPNN README · ThermoMPNN paper. “—” means we couldn't verify it.
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