← Protein structure & design

SaProt

Protein language model with a structure-aware vocabulary combining amino acids with Foldseek 3Di tokens.

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CategoryProtein structure & design
GitHubwestlake-repl/SaProt
First public2023-10-02 (source)
Paperhttps://doi.org/10.1101/2023.10.01.560349 · bioRxiv preprint
LicenseMIT
PricingOpen source
Tags#alphafold2#foldseek#predicted-structures
Last checked2026-10-16

Specs

TaskEmbeddings, fitness and property prediction
ModalitiesSequence + 3Di structure tokens
MSA requiredNo
Open weightsYes (35M-1.3B)
GPU needGPU recommended
GitHub stars639
Interface—

Specs come from each project's README, paper or official page · SaProt README · SaProt paper. “—” means we couldn't verify it.

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