ProteinMPNN
Deep-learning inverse folding: designs sequences for given backbones.
| Category | Protein structure & design |
|---|---|
| GitHub | dauparas/ProteinMPNN |
| First public | 2022-06-04 (source) |
| Paper | https://www.science.org/doi/10.1126/science.add2187 |
| License | MIT |
| Pricing | Open source |
| Tags | #inverse-folding#design |
| Last checked | 2026-10-16 |
Specs
| Task | Inverse folding (sequence design) |
|---|---|
| Modalities | Protein, single or multiple chains |
| MSA required | — |
| Open weights | Yes (in repo) |
| GPU need | — |
| GitHub stars | 1,879 |
| Interface | Package |
Specs come from each project's README, paper or official page · ProteinMPNN README · ProteinMPNN paper. “—” means we couldn't verify it.
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