OpenFold
Trainable open-source reproduction of AlphaFold2 in PyTorch.
| Category | Protein structure & design |
|---|---|
| GitHub | aqlaboratory/openfold |
| First public | 2021-11-18 (source) |
| Paper | https://www.nature.com/articles/s41592-024-02272-z |
| License | Apache-2.0 |
| Pricing | Open source |
| Tags | #structure#pytorch |
| Last checked | 2026-10-16 |
Specs
| Task | Structure prediction (trainable AlphaFold2) |
|---|---|
| Modalities | — |
| MSA required | — |
| Open weights | Yes (Apache 2.0) |
| GPU need | — |
| GitHub stars | 3,440 |
| Interface | — |
Specs come from each project's README, paper or official page · OpenFold README · OpenFold site. “—” means we couldn't verify it.
Compare with…
Pick 1–3 other Protein structure & design tools to compare side by side with OpenFold.
Related
Structure prediction of proteins, nucleic acids, ligands and their complexes; free web server and code, weights on request for non-commercial use.
Protein structure & designFree (research)#structure#complexes
200M+ predicted protein structures from DeepMind and EMBL-EBI.
Protein structure & designOpen source#database#structure
Diffusion model for de novo protein backbone design and binder design.
Protein structure & designOpen source#design#diffusion