← Drug discovery & molecules

Nesso-1

Recursion's Apache-2.0 co-folding model for fast protein–ligand binding-affinity prediction.

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CategoryDrug discovery & molecules
GitHubrecursionpharma/nesso
First public2026-08-03 (source)
Paperhttps://doi.org/10.64898/2026.08.01.742196
LicenseApache-2.0
PricingOpen source
Tags#binding-affinity#co-folding
Last checked2026-10-16

Specs

TaskBinding affinity prediction (coarse-grained co-folding)
Molecular representationProtein sequence + ligand SMILES
Open weightsYes (Hugging Face)
GitHub stars—
Interface—

Specs come from each project's README, paper or official page · Nesso-1 README. “—” means we couldn't verify it.

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