MassNet (XuanjiNovo)
AI-ready DDA mass-spectrometry corpus (1.54B MS/MS spectra, 548M PSMs, 35 species) in a Parquet tensor format (MSDT), plus XuanjiNovo, a non-autoregressive transformer for de novo peptide sequencing trained on 100M PSMs.
| Category | Proteomics & metabolomics |
|---|---|
| GitHub | guomics-lab/MassNet-DDA |
| First public | 2025-06-04 (source) |
| Paper | https://doi.org/10.1038/s41592-026-03247-y · Nature Methods (2026) |
| Code license | Apache-2.0 |
| Weights license | code and XuanjiNovo weights Apache-2.0 (per paper and repo LICENSE) |
| What this allows | Permissive (commercial OK) Use, modify and ship it inside closed-source commercial products; keep the license text and copyright notices. What do these mean? |
| License source | github.com/guomics-lab/MassNet-DDA/blob/main/LICENSE · checked 2026-10-19 |
| Pricing | Open source |
| Tags | #mass-spec#de-novo#dataset#transformer |
| Last checked | · links verified |
Can I use MassNet (XuanjiNovo) commercially?
Yes. The recorded license is permissive, so closed-source commercial use is allowed if you keep the notices.
- Code: Apache-2.0
- Weights: code and XuanjiNovo weights Apache-2.0 (per paper and repo LICENSE)
- Source: github.com/guomics-lab/MassNet-DDA/blob/main/LICENSE · license checked 2026-10-19
What the license types mean · not legal advice.
Specs
| Acquisition (DDA / DIA) | DDA LC-MS/MS from 10+ high-resolution platforms |
|---|---|
| Task | De novo peptide sequencing (XuanjiNovo); also supports RT prediction and PSM rescoring |
| Input | MS/MS spectra in MSDT (MSDT-Converter reads mzML, MGF, Bruker .d) |
| GitHub stars | 11 |
| Interface | — |
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