Efficient Evolution
Uses general protein language models to recommend affinity-improving mutations, applied to human antibodies.
| Category | Protein structure & design |
|---|---|
| GitHub | brianhie/efficient-evolution |
| First public | 2022-04-10 (source) |
| Paper | https://doi.org/10.1038/s41587-023-01763-2 · Nature Biotechnology (2024) |
| License | MIT |
| Pricing | Open source |
| Tags | #protein |
| Last checked | 2026-10-16 |
Specs
| Task | Mutation recommendation / directed evolution |
|---|---|
| Modalities | Sequence |
| MSA required | No |
| Open weights | Uses ESM models |
| GPU need | CPU or GPU |
| GitHub stars | 227 |
| Interface | — |
Specs come from each project's README, paper or official page · Efficient Evolution README · Efficient Evolution paper. “—” means we couldn't verify it.
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