← Bio LLM agents & copilots

Chaperone

Baker lab harness that wires 50+ protein design, folding and analysis tools into reproducible SLURM pipelines and ships agent skills so coding agents can build and run design campaigns.

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CategoryBio LLM agents & copilots
GitHubRosettaCommons/chaperone
First public2026-10-20 (source)
Paperhttps://doi.org/10.64898/2026.10.19.759896 · bioRxiv preprint (2026)
Code licenseMIT
License notecode MIT
What this allowsPermissive (commercial OK)
Use, modify and ship it inside closed-source commercial products; keep the license text and copyright notices. What do these mean?
License sourcegithub.com/RosettaCommons/chaperone/blob/main/LICENSE · checked 2026-10-22
PricingOpen source
Tags#agent#protein-design#pipeline#hpc
Last checked · links verified

Can I use Chaperone commercially?

Yes. The recorded license is permissive, so closed-source commercial use is allowed if you keep the notices.

What the license types mean · not legal advice.

Specs

Model backboneAny coding agent
Tools / actionsRFD3, BindCraft, BoltzGen, ProteinMPNN, AF3, Boltz2, Chai1 and other blocks; SLURM orchestration
Wet-lab integration—
GitHub stars117
InterfacePython package with AGENTS.md and agent skills (Claude Code, Codex)

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