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Cell2Sentence (C2S-Scale)

Turns expression profiles into ranked gene "cell sentences" so LLMs (up to 27B) can model and generate single-cell data.

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CategorySingle-cell & foundation models
GitHubvandijklab/cell2sentence
First public2023-09-14 (source)
Paperhttps://doi.org/10.1101/2023.09.11.557287 · bioRxiv preprint
LicenseApache-2.0
PricingOpen source
Tags#single-cell
Last checked2026-10-16

Specs

Pretraining corpus57M+ human and mouse cells (CELLxGENE, HCA) plus text
ArchitectureLLMs (Pythia, Gemma) on cell sentences
TasksCell generation, annotation, perturbation, QA
SpeciesHuman, mouse
GitHub stars889
Interface—

Specs come from each project's README, paper or official page · Cell2Sentence (C2S-Scale) README · Cell2Sentence (C2S-Scale) paper. “—” means we couldn't verify it.

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